Capillary morphogenesis protein 2
WebDec 5, 2016 · Here, we discovered that EphA2, a member of the large family of Ephrin receptor tyrosine kinases, is a functional signaling receptor for progranulin. Recombinant progranulin bound with high affinity to EphA2 in both solid phase and solution. WebApr 4, 2014 · Capillary morphogenesis gene 2 (CMG2), also known as anthrax toxin receptor 2, has been indicated in the formation of new vasculature and in the …
Capillary morphogenesis protein 2
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WebMar 29, 2024 · The Capillary Morphogenesis Gene 2 Triggers the Intracellular Hallmarks of Collagen VI-Related Muscular Dystrophy. Anthrax toxin receptor 2 is a potential … WebPA binds to either of two receptors, capillary morphogenesis protein-2 (CMG-2) or tumor endothelial marker-8 (TEM-8), which triggers the binding and cytoplasmic translocation of LF and EF. However, the distribution of functional TEM-8 and CMG-2 receptors during anthrax toxin intoxication in animals has not been fully elucidated.
WebFeb 23, 2024 · Capillary morphogenesis protein 2 (CMG2) was originally identified through its participation in capillary morphogenesis, and subsequently identified as the second … WebMar 21, 2024 · IFT74 (Intraflagellar Transport 74) is a Protein Coding gene. Diseases associated with IFT74 include Joubert Syndrome 40 and Spermatogenic Failure 58.Among its related pathways are Organelle biogenesis and maintenance and Bardet-Biedl syndrome.Gene Ontology (GO) annotations related to this gene include chromatin …
WebThis condition is due to mutations in the anthrax toxin receptor-2 ( ANTXR2) gene. This gene is also known as capillary morphogenesis protein-2. This gene is located on the long arm of chromosome 4 (4q21.21). Management [ edit] There is no presently known curative treatment for this condition. [citation needed] Management is supportive WebApr 4, 2003 · However, in this report we identify the human capillary morphogenesis protein 2 (CMG2) as a second anthrax toxin receptor. CMG2 is the protein most similar …
WebDetects human CMG‑2/ANTXR2 in direct ELISAs and Western blots. In direct ELISAs and Western blots, approximately 20% cross-reactivity with recombinant mouse CMG-2 is observed. Source Polyclonal Goat IgG Purification Antigen Affinity-purified Immunogen Mouse myeloma cell line NS0-derived recombinant human CMG‑2/ANTXR2 isoform 1 …
WebThere are two known homologous receptors, which bind to PA83, called tumor endothelium marker-8 ( TEM8) and capillary morphogenesis protein 2 ( CMG2 ). [3] Then a 20 kDa fragment (PA20) is cleaved off … free field trip permission slip templatefree field trips for kids in philadelphiaWebA complex role of anthrax toxin receptor 2 polymorphisms and capillary morphogenesis protein 2 in ankylosing spondylitis pathogenesis A complex role of anthrax toxin receptor 2 polymorphisms and capillary morphogenesis protein 2 in ankylosing spondylitis pathogenesis doi: 10.1007/s10067-015-3158-9. Epub 2016 Jan 4. Authors free field trips for schoolsWebDec 27, 2012 · DOI: 10.3390/toxins5010001. Abstract. Tumor endothelium marker-8 (TEM8) and capillary morphogenesis protein-2 (CMG2) are the two well-characterized anthrax … free field trips for studentsWebSep 1, 2005 · The CMG2 gene, which has been shown to be broadly expressed in different tissues ( 4 ), encodes three protein isoforms, two of which, CMG2 488 and CMG2 489, … free field trip svgWebHere, we established mice with CMG2 only expressed in tumor endothelial cells (ECs) and determined the specific contribution of tumor stromal ECs to the toxin’s antitumor activity. Our results demonstrate that disruption of ERK signaling only within tumor ECs is sufficient to halt tumor growth. free field trips in chicagoWebCapillary morphogenesis protein-2 is the major receptor mediating lethality of anthrax toxin in vivo Shihui Liu1, Devorah Crown, Sharmina Miller-Randolph, Mahtab Moayeri, … free fier ia