Cdk5 regulatory subunit-associated protein 3
WebJan 9, 2015 · Cdk5rap3 was overexpressed following subacute heart failure induced by adrenalin and following ischemia induced by coronary artery ligation. It was expressed … WebCdk5rap3 CDK5 regulatory subunit associated protein 3 [ (house mouse)] Gene ID: 80280, updated on 26-Sep-2024 Summary Enables ubiquitin-like protein ligase binding …
Cdk5 regulatory subunit-associated protein 3
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WebSubstrate adapter for ufmylation, the covalent attachment of the ubiquitin-like modifier UFM1 to substrate proteins, in response to endoplasmic reticulum stress. Negatively regulates NF-kappa-B-mediated gene transcription through the control of RELA phosphorylation. Probable tumor suppressor initially identified as a CDK5R1 interactor controlling cell … WebCDK5 regulatory subunit-associated protein 2 is a protein that in humans is encoded by the CDK5RAP2 gene. It has necessary roles in the formation and stability of …
WebCDK5 regulatory subunit-associated protein 3, CDK5 activator-binding protein C53 GeneRIFs: Gene References Into Functions The current findings advance innovation in … WebMar 29, 2024 · CDK5RAP3 as tumour suppressor negatively regulates self-renewal and invasion and is regulated by ERK1/2 signalling in human gastric cancer. The current …
WebCDK5 regulatory subunit-associated protein 1-like 1 (CDKAL1) is a protein-coding gene involved in post-transcriptional RNA modification. 7 Genome-wide association studies … WebCDK5 regulatory subunit associated protein 3: RGD ID: 1616671: MGI Page: MGI: Description: Enables ubiquitin-like protein ligase binding activity. Involved in several processes, including definitive erythrocyte differentiation; liver development; and protein ufmylation. Acts upstream of or within positive regulation of transcription by RNA ...
WebSep 26, 2024 · Cdk5rap2 CDK5 regulatory subunit associated protein 2 [ (house mouse)] Gene ID: 214444, updated on 26-Sep-2024 Summary Predicted to enable several …
WebNX_Q96SN8 - CDK5RAP2 - CDK5 regulatory subunit-associated protein 2 - Function. Potential regulator of CDK5 activity via its interaction with CDK5R1. Negative regulator of centriole disengagement (licensing) which maintains centriole engagement and cohesion. Involved in regulation of mitotic spindle orientation (By similarity). Plays a role in the … mwt of feWebFeb 27, 2024 · The CDK5RAP2 gene encodes a centrosomal protein that localizes to the spindle poles during mitosis (summary by Hassan et al., 2007 and Lizarraga et al., 2010 … mwt of h2oWebNCBI Full Gene Name CDK5 regulatory subunit associated protein 3; NCBI Gene Aliases C53, HSF-27, IC53, LZAP, MST016, OK/SW-cl.114, PP1553; Target CDK5RAP3; Vector Name pLenti-C-Myc-DDK; Molecular Weight 1518 bp; Selectable Marker Chloramphenicol (34 ug/mL) Conjugate/Tag/Label Myc-DDK; Species Human; how to overcome opioid addictionWebMar 21, 2024 · Heterodimer composed of a catalytic subunit CDK5 and a regulatory subunit CDK5R1 (p25) and macromolecular complex composed of at least CDK5, CDK5R1 (p35) and CDK5RAP1 or CDK5RAP2 or CDK5RAP3. ... Phosphorylates also exocytosis associated proteins such as MCAM/MUC18, SEPT5, SYN1, and CDK16/PCTAIRE1 as … how to overcome our biases ted talk summaryWebMay 17, 2024 · Mitochondrial dysfunction is associated with aging and age-related hearing loss (AHL). However, the precise mechanisms underlying the pathophysiology of hearing … how to overcome osteoarthritisWebMar 29, 2024 · This gene encodes a regulator of CDK5 (cyclin-dependent kinase 5) activity. The protein encoded by this gene is localized to the centrosome and Golgi complex, … mwt of hclWebApr 15, 2011 · The CDK5 kinase regulatory subunit-associated protein 3 (CDK5RAP3 or C53/LZAP) regulates apoptosis induced by genotoxic stress. Although CDK5RAP3 has been implicated in cancer progression, its exact role in carcinogenesis is not well established. In this article, we report that CDK5RAP3 has an important prometastatic function in ... how to overcome our biases ted talk