G3bp2 phosphorylation
WebMay 15, 2012 · G3BP2 regulates LRP6 phosphorylation. (A) F9 cells were treated with either control siRNA or G3BP2-specific siRNA for 24 hours, followed by another round of … WebRIOK1 phosphorylates G3BP2 at Thr226, which increases the activity of G3BP2. RIOK1-mediated phosphorylation of G3BP2 facilitated ubiquitination of p53 by murine double …
G3bp2 phosphorylation
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WebRas-GAP SH3 domain binding proteins (G3BPs) are a family of RNA-binding proteins that include G3BP1 and G3BP2 in mammals. The protein structure of G3BP2 allows it to bind with RNA or protein and regulate the nucleoplasmic shuttle, therefore participating in a variety of biological functions such as cell growth, differentiation and migration, and RNA … • Kim MM, Wiederschain D, Kennedy D, Hansen E, Yuan ZM (June 2007). "Modulation of p53 and MDM2 activity by novel interaction with Ras-GAP binding proteins (G3BP)". Oncogene. 26 (29): 4209–15. doi:10.1038/sj.onc.1210212. PMID 17297477. • Olsen JV, Blagoev B, Gnad F, Macek B, Kumar C, Mortensen P, Mann M (November 2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell. 127 (3): 635–48. doi:10.1016/j.cell.2006.…
WebJan 4, 2024 · Neither FMDV nor ERAV L pro interfered with phosphorylation of RNA-dependent protein kinase (PKR) or eIF2α, indicating that L pro does not affect SG formation by inhibiting the PKR-triggered signaling cascade. Taken together, our data suggest that aphthoviruses actively target scaffolding proteins G3BP1 and G3BP2 and antagonize SG … WebHeat shock-induced stress granule assembly and phosphorylation of eIF2a are suppressed following downregulation of ... G3BP2 immunoprecipitates were probed with different PKCa antibodies (Fig. 2 ...
WebMay 21, 2024 · Wnt3a-stimulated LRP6 phosphorylation is dependent upon arginine methylation of G3BP2. J Cell Sci. 2012;125(Pt 10):2446–56. CAS PubMed PubMed Central Google Scholar WebApr 14, 2024 · G3BP2, a homolog of G3BP1, is also expressed in many tissues and cell lines, ... UBAP2L knockdown did not affect stress-induced eIF2α phosphorylation or translation inhibition, indicating that ...
WebSH3BP2 deficiency/cherubism. The SH3-binding protein (SH3BP2) is an adaptor protein expressed in most cell types with a role in regulation of various signal transduction …
WebMar 6, 2024 · The reduction of G3BP2 protein by USP7 knockdown could be due to the decreased G3BP2 stability (Fig. 2K), suggesting that USP7 stabilized G3BP2 by inhibiting its degradation through proteasome. We ... diy steampunk shelvesWebAug 17, 2024 · Intriguingly, we also observed that G3BP2 overexpression facilitated p65 phosphorylation and simultaneously downregulated the protein level of IκBα (Supplementary Material Figure S5), which ... diy steampunk ideasWebJan 30, 2024 · The initial formation of SGs correlates with and requires phosphorylation of eukaryotic translation initiation factor 2 subunit α (eIF2α) as SGs do not form in mouse embryonic fibroblasts expressing a mutant form of eIF2α that cannot be phosphorylated. ... The recruitment of G3BP1 and its homolog G3BP2 by nsP3 into cytoplasmic foci benefits ... diy steampunk light projectscranston mechanicWebApr 20, 2015 · Interestingly, the tyrosine residue Tyr 103 (Tyr 107 in murine Twist1), which lies within the identified G3BP2-binding motif of human TWIST1, is predicted as a potential phosphorylation site. diy steam room showerWeb 第 6 年 经营模式：经销商 商铺产品：9983条 所在地区：上海上海市 注册时间：2024-04-17 最近登录：2024-04-14 diy steel investment castingWebAug 17, 2024 · Furthermore, consistent with the high similarity between the NTF2 domains of G3BP1 and G3BP2, N protein of SARS-CoV-2 interacts with G3BP2 in a similar … cranston milton cat