Small cholangiocyte
Webb15 apr. 2016 · Unless noted otherwise, a small cholangiocyte cell line was used for spheroid culture as described previously. 19 Primary neonatal extrahepatic cholangiocytes were isolated by outgrowth from 0- to 3-day-old BALB/c mouse pup bile ducts as described previously and were used for spheroids when specified. 20 Primary cells were used at … Webb16 nov. 2024 · Importantly, we can combine top-down and bottom-up approaches to engineer both large (300 µm) and smaller self-assembled branched cholangiocyte …
Small cholangiocyte
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Webb11 nov. 2024 · With this level of maturation, these cholangiocytes are amenable for testing the efficacy of cystic fibrosis drugs and for studying the role of cilia in cholangiocyte … Webb27 nov. 2003 · Aims: We have shown that large and small cholangiocytes, which reside primarily in large and small intrahepatic bile ducts, respectively, have different functions and responses to injuries. However, there are no systematic studies of the molecular differences between small and large cholangiocytes, which would explain cholangiocyte …
Webb5 maj 2024 · Primary neonatal (3 days old) extrahepatic cholangiocytes or a small intrahepatic cholangiocyte cell line (SBEC) were used for 2D or 3D spheroid culture as … Webb12 juni 2024 · Interestingly, cholangiocyte-enriched transcription factors, Onecut1 and Onecut2, and cholangiocyte markers, Gpbar1 and Spp1, were significantly up-regulated in the HFM culture (figure 4(D)). Immunofluorescence analysis also confirmed that HFM-cultured CLCs maintained the expression of cholangiocyte markers (HNF1B, AQP1, …
WebbWe found that both small and large cholangiocytes expressed GABA receptors. GABA: (i) induced apoptosis of large cholangiocytes and reduced large IBDM; (ii) decreased … Webb1 aug. 2008 · The stimulation of small cholangiocyte proliferation by HTMT dimaleate was blocked by the HRH1 antagonist terfenadine , the intracellular Ca 2+ chelator BAPTA/AM …
WebbSmall and large cholangiocytes express HRH1, CaMK I, and CaMK II. Small (but not large) cholangiocytes proliferate in response to HTMT dimaleate and are blocked by …
Webb9 feb. 2024 · Cholangiocyte injury causes cholestasis, including primary biliary cholangitis (PBC). However, the etiology of PBC remains unclear despite being characterized as an … reaching hearts sda listen liveWebbSmall and large cholangiocytes differ in nuclear-to-cytoplasmic ratio; small cholangiocytes have a higher ratio, suggesting they are less differentiated and have more capacity for … reaching hearts international live streamWebb17 mars 2010 · However, in the CCl 4 model of hepatotoxin induced liver damage both normal and BDL cholangiocytes are susceptible to damage. 39,40 Administration of an acute dose of CCl 4 to normal or BDL rats induces apoptosis of large cholangiocytes 39,40 (which line large ducts). 82,83 Small cholangiocyte (which line small ducts) 82,83 were … reaching hearts international mdWebbNational Center for Biotechnology Information reaching hearts internationalWebb9 feb. 2024 · Collectively, DUOX2+ACE2+ small cholangiocytes are pathogenic targets in PBC, and preservation of DUOX2+ACE2+ cholangiocytes and targeting anti-pIgR … reaching heaven with our song satb pdfWebb8 mars 2024 · Cholangiocytes, the epithelial cells lining the intrahepatic and extrahepatic bile ducts, are highly specialized cells residing in a complex anatomic niche where they … how to start a shop on amazonWebb25 aug. 2024 · Small cell cholangiocytes (SMCCs) were plated at 2 × 10 5 cells/well in a six-well plate and transfected with 2.5 µg control or Wnt7b plasmid, described elsewhere, and 50 µM negative or β-catenin small interfering RNA (siRNA; Thermo Fisher Scientific, Waltham, MA) using Lipofectamine 3000 (Invitrogen, Carlsbad, CA), as per the … how to start a shoes business